This book delves into the burgeoning field of nano-biomaterials and their application in targeted drug delivery across various therapeutic domains. Through its comprehensive exploration, it offers insights into the innovative approaches and potential of biomaterial-inspired nanomedicines in revolutionizing healthcare.  Chapter 1 introduces readers to the fundamental concepts of biomaterial-inspired nanomedicines, laying the groundwork for subsequent discussions. Chapter 2 delves into the utilization of nano-biomaterials in tissue engineering, highlighting their role in regenerative medicine. The book further examines the targeting of specific physiological barriers, such as the blood-brain barrier (Chapter 3), and explores the opportunities and challenges in biomaterial-based vaccine delivery (Chapter 4). Additionally, it discusses the use of nano-biomaterials in addressing pulmonary obstruction (Chapter 5) and targeting the tumor microenvironment for chemotherapy (Chapter 6). Chapters 7 to 16 explore various therapeutic applications of nano-biomaterials across different medical conditions, including autoimmune skin disorders, diabetes, wound healing, central nervous system disorders, ocular diseases, infectious diseases, musculoskeletal disorders, and gastrointestinal diseases. Furthermore, the book sheds light on advances in nano-biomaterials for effective antimicrobial therapy and offers insights into the clinical and regulatory considerations associated with their use (Chapter 17). By encompassing a wide range of topics and providing in-depth analyses, "Biomaterial-Inspired Nanomedicines for Targeted Therapies" serves as a valuable resource for researchers, practitioners, and policymakers aiming to leverage the potential of nano-biomaterials in improving healthcare outcomes.